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Pharmacology
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Pharmacogenetics
HLA-B*5701
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Virology
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Immunology
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Pharmacology
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THERAPEUTIC DRUG MONITORING

Therapeutic drug monitoring is used to optimise drug regimens for the individual patient by increasing efficacy and avoiding drug-related toxicity. Prospective surveys suggest 20% patients in clinic have sub-therapeutic plasma concentrations of PIs and NNRTIs, while the inter-individual variability in plasma concentrations is immense (≥100-fold difference) despite standard dosing.

To review Liverpool HIV Pharmacology Group drug interactions web-site: LHPG

HIV Drugs
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Protease Inhibitor




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NNRTI

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NtRTI
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Fusion Inhibitor
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Integrase Inhibitor
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CCR5 Antagonist

Amprenavir
Atazanavir
Darunavir
Indinavir
Lopinavir
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Efavirenz
Etravirine
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Tenofovir
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Enfuvirtide (T-20)
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Raltegravir
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Maraviroc

Nelfinavir
Ritonavir
Saquinavir
Tipranavir

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Nevirapine
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HCV Drugs
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Nucleoside analogue
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NtRTI

Ribavirin
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Tenofovir

 
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Pharmaceutical Schemes
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Therapeutic drug monitoring is sponsored by the following pharmaceutical company for the drug / patient category listed. Please contact your MSD representative for full details. The company will be invoiced directly for the cost of the analysis.

Merck Sharpe & Dohme: Indinavir in cases of suspected toxicity
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Lab21 Healthcare. Updated January 2010.

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